6-Br-APB is a synthetic and selective dopamine D<sub>1</sub> receptor agonist and stimulant-like drug of the 3-benzazepine family. It is a cyclized phenethylamine and modified derivative of the monoamine neurotransmitter dopamine. The (R)-enantiomer is a potent dopamine D<sub>1</sub> receptor full agonist, while the (S) enantiomer retains selectivity but is a weak partial agonist of the receptor. (R)-6-Br-APB and similar dopamine D<sub>1</sub> receptor-selective full agonists like SKF-81,297 and SKF-82,958 produce characteristic anorectic effects, stereotyped behaviour, and self-administration in animals, with a similar but not identical profile to that of dopaminergic stimulants such as amphetamine.