The enzyme 5-dehydro-4-deoxyglucarate dehydratase () catalyzes the chemical reaction
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5-dehydro-4-deoxy-<small>D</small>-glucarate hydro-lyase (decarboxylating 2,5-dioxopentanoate-forming). Other names in common use include 5-keto-4-deoxy-glucarate dehydratase, deoxyketoglucarate dehydratase, <small>D</small>-4-deoxy-5-ketoglucarate hydro-lyase, and 5-dehydro-4-deoxy-<small>D</small>-glucarate hydro-lyase (decarboxylating). This enzyme participates in ascorbate and aldarate metabolism.