In enzymology, a 5-aminopentanamidase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are 5-aminopentanamide and H<sub>2</sub>O, whereas its two products are 5-aminopentanoate and NH<sub>3</sub>.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 5-aminopentanamide amidohydrolase. Other names in common use include 5-aminovaleramidase, and 5-aminonorvaleramidase. This enzyme participates in lysine degradation.