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5-HT1F receptor

5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT<sub>1</sub> receptor protein and also denotes the human gene encoding it.

Agonists

  • 5-n-Butyryloxy-DMT: >60-fold selectivity versus 5-HT<sub>1E</sub> receptor
  • BRL-54443 - mixed 5-HT<sub>1E/1F</sub> agonist
  • Eletriptan - mixed 5-HT<sub>1B/1D/1E/1F/2B/7</sub> agonist
  • LY-334,370 - as well as related benzamides
  • LY-344,864 (N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide)
  • Naratriptan - mixed 5-HT<sub>1B/1D/1F</sub> agonist
  • Lasmiditan - selective 5-HT<sub>1F</sub> agonist, a first-in-class ditan molecule

Antagonists

MLS000756415

See also

References

Further reading

External links