5,6-MDO-DMT, or 5,6-methylenedioxy-N,N-dimethyltryptamine, is a lesser-known chemical compound of the tryptamine family. It is the 5,6-methylenedioxy derivative of dimethyltryptamine (DMT) and is an analogue of 5-MeO-DMT. In his 1991 book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin lists the dose as greater than 5mg smoked and the duration as unknown. 5,6-MDO-DMT produced no effects whatsoever at a dose of 5mg smoked. Higher doses were not assessed. Very little data exists about the pharmacological properties, metabolism, and toxicity of 5,6-MDO-DMT. Its chemical synthesis has been described. 5,6-MDO-DMT was first described in the scientific literature by Toni B. Kline and colleagues in 1982.