4-chlorophenylacetate 3,4-dioxygenase () is an enzyme that catalyzes the chemical reaction
The four substrates of this enzyme are 4-chlorophenylacetic acid, reduced nicotinamide adenine dinucleotide (NADH), oxygen, and a proton. Its products are 3,4-dihydroxyphenylacetic acid, oxidised NAD<sup>+</sup>, and hydrochloric acid.
This enzyme is an oxidoreductase, which uses molecular oxygen as oxidant and incorporates both its atoms into the starting material. The systematic name of the enzyme class is 4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating). It is an ironâÂÂsulfur protein that is part of tyrosine metabolism.