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4-Methylcathinone

4-Methylcathinone (4-MC), also known as normephedrone is a stimulant drug of the cathinone group. It is an active metabolite of the better known drug mephedrone (4-methylmethcathinone or 4-MMC).

4-MC is a serotonin–norepinephrine–dopamine releasing agent (SNDRA) similarly to mephedrone. It displays a 2.4-fold selectivity to promote monoamine release via DAT over SERT as opposed to 309-fold selectivity for cathinone. It also releases norepinephrine.

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