4â²-Demethylrebeccamycin synthase (EC 4.3.3.5, arcyriaflavin A N-glycosyltransferase, RebG) is an enzyme with systematic name 4â²-demethylrebeccamycin <small>D</small>-glucose-lyase. It catalyses the following chemical reaction
This is a late step in the biosynthesis of rebeccamycin.