4â²,7-Dihydroxyflavone is a flavone. It is found in Medicago truncatula in relation with the root nodulation symbiont Sinorhizobium meliloti or in seeds of Sophora viciifolia.
Like many other flavonoids, 4â²,7-dihydroxyflavone has been found to possess activity at opioid receptors in vitro. Specifically, it acts as an antagonist of the ü-opioid receptor and, with lower affinity, of the ú- and ô-opioid receptors.