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3-oxoacyl-(acyl-carrier-protein) reductase (NADH)

In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) () is an enzyme that catalyzes the chemical reaction

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NAD<sup>+</sup> 3-oxoacyl-[acyl-carrier-protein] + NADH + H<sup>+</sup>

Thus, the two substrates of this enzyme are (3R)-3-hydroxyacyl-[acyl-carrier-protein] and NAD<sup>+</sup>, whereas its 3 products are 3-oxoacyl-[acyl-carrier-protein], NADH, and H<sup>+</sup>.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD<sup>+</sup> oxidoreductase. Other names in common use include 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine, dinucleotide) reductase, and 3-oxoacyl-[acyl-carrier-protein] reductase (NADH).

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