3-hydroxypropionate dehydrogenase

In enzymology, a 3-hydroxypropionate dehydrogenase () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are 3-hydroxypropionic acid and oxidised nicotinamide adenine dinucleotide (NAD⁺). Its products are 3-oxopropanoic acid, reduced NADH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 3-hydroxypropanoate:NAD⁺ oxidoreductase. This enzyme participates in beta-alanine metabolism and propanoate metabolism.

See also

• 3-hydroxypropionate dehydrogenase (NADP+) which catalyses the same reaction with an alternative cofactor

References