3-hydroxy-<small>D</small>-aspartate aldolase (, <small>D</small>-3-hydroxyaspartate aldolase) is an enzyme with systematic name 3-hydroxy-<small>D</small>-aspartate glyoxylate-lyase (glycine-forming). This enzyme catalyses the following chemical reaction
This enzyme is a pyridoxal-phosphate protein.