3-Pyrrolylpropylamine, also known as ñ-methyl-3-pyrrolylethylamine, is a chemical compound of the arylalkylamine family. It is the analogue of the serotonergic psychedelic ñ-methyltryptamine (AMT) in which the benzene component of the indole ring has been removed.
In contrast to tryptamines like AMT, 3-pyrrolylpropylamine does not bind to the serotonin 5-HT<sub>1A</sub> or 5-HT<sub>2A</sub> receptors (K<sub>i</sub> = >10,000nM). These findings suggest that the benzene part of the indole ring is required for significant binding to serotonin receptors and by extension psychedelic activity. The activities of 3-pyrrolylpropylamine at other targets, such as the monoamine transporters, were not reported.
3-Pyrrolylpropylamine was first described in the scientific literature by at least 1990.