The 2nd Mississippi Legislature first met on January 4, 1819, in Natchez, Mississippi. It adjourned in February 1819.
The Mississippi State Senate was composed of the following members. Lieutenant Governor Duncan Stewart served ex officio as President of the Senate, and non-senator Spotswood Mills served as the Senate's secretary.
The Mississippi House of Representatives was composed of the following. Edward Turner was elected Speaker of the House. Non-representatives Peter A. Vandorn and Henry Vaughan served as Clerk and Doorkeeper respectively.