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23S rRNA (uridine2479-2'-O)-methyltransferase

23S rRNA (uridine<sup>2479</sup>-2'-O)-methyltransferase (, AviRb) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (uridine<sup>2479</sup>-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + uridine<sup>2479</sup> in 23S rRNA S-adenosyl-L-homocysteine + 2'-O-methyluridine<sup>2479</sup> in 23S rRNA

Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis.

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