23S rRNA (guanine<sup>2069</sup>-N<sup>7</sup>)-methyltransferase (, rlmK (gene), 23S rRNA m7G2069 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine<sup>2069</sup>-N<sup>7</sup>)-methyltransferase. This enzyme catalyses the following chemical reaction
The enzyme specifically methylates guanine<sup>2069</sup> at position N<sup>7</sup> in 23S rRNA.