23S rRNA (adenine<sup>2085</sup>-N<sup>6</sup>)-dimethyltransferase (, ErmC' methyltransferase, ermC methylase, ermC 23S rRNA methyltransferase, rRNA:m<sup>6</sup>A methyltransferase ErmC', ErmC', rRNA methyltransferase ErmC' ) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine<sup>2085</sup>-N<sup>6</sup>)-dimethyltransferase. This enzyme catalyses the following chemical reaction
ErmC is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalysing the methylation of 23S rRNA at adenine<sup>2085</sup>.