The 21st Actors and Actresses Union Awards ceremony was held on 18 June 2012 at the Teatro Circo Price in Madrid. The gala was hosted by Yayo Cáceres.
In addition to the competitive awards the association 'Madres unidas contra la droga' and activist Alejandra Soler Gilabert received the award, Concha Velasco the career award and the Special Award went to the Association for the Recovery of Historical Memory and the .
The winners and nominees are listed as follows: