The 2025 Women's Challenge Cup (sponsored as the Betfred Women's Challenge Cup) was the 13th staging of the Rugby Football League's cup competition for women's rugby league clubs.
The competition used a slightly different format from 2024. Although the group stage plus knockout rounds format was retained, the number of teams in the competition was reduced from 16 to 12.
The group stage saw four groups of three competing in a single round robin with the group matches played over three consecutive weekends in April 2025. The group winners and runners-up advanced to the knockout rounds. The quarter-finals were played on the last weekend in April. The semi-finals were double headers with the semi-finals of the men's tournament on the weekend of 10/11 May 2025, and the final was played at Wembley Stadium, London on 7 June 2025 alongside the finals of the men's competition and the 1895 Cup.
St Helens, winners in 2024, were seeded together with Leeds Rhinos, Wigan Warriors and York Valkyrie. These four, pool 2, were in different groups in the group stage. The other eight teams formed pool 1 with two being drawn in each group.
The draw for the group stages was made on 14 January.
The groups were drawn as follows:
The fixture list for the group stage was announced on 10 March 2025.
The quarter-finals took place over the weekend of 26/27 April.
The semi-finals were played over the weekend of 10/11 May and were double-headers with the men's semi-finals. Both matches were broadcast live on the BBC iPlayer.
The final took place on Saturday 7 June 2025, as part of a triple header, alongside the Men's final, and the 1895 Cup final.