The 2025 UTSA Roadrunners football team represented the University of Texas at San Antonio (UTSA) as a member of the American Conference during the 2025 NCAA Division I FBS football season. Led by sixth-year head coach Jeff Traylor, the Roadrunners played their home games at the Alamodome in San Antonio.
The UTSA Roadrunners drew an average home attendance of 24,361, the 87th-highest of all NCAA Division I FBS football teams.
The American Athletic Conference announced the 2025 football conference opponents for the Roadrunners on August 15, 2024. On July 25, 2024, UTSA completed their scheduling of nonconference opponents with a game against Incarnate Word from the Southland Conference. The other three opponents includes games against, Colorado State from the Mountain West Conference, Texas A&M from the Southeastern Conference and rival Texas State from the Sun Belt Conference.
Over the offseason, UTSA lost 13 players through the NCAA transfer portal. Eleven are currently committed while the other is still actively pursuing new schools. Additionally UTSA gained 14 commitments via the portal