The 2025 Syracuse Orange football team represented Syracuse University as a member of the Atlantic Coast Conference (ACC) during the 2025 NCAA Division I FBS football season. The Orange played their home games at the JMA Wireless Dome located in Syracuse, New York. They were led by second-year head coach Fran Brown. The Orange were in their 124th season overall and their 13th as a member of the ACC. Though they started the season 3-1, the Orange would end the season on a 8 game losing streak finishing last in conference play. This was mainly due to starting quarterback Steve Angeli tearing his Achilles during the in-conference game versus Clemson where they upset the Tigers 34-21.
The Syracuse Orange drew an average home attendance of 38,605, the highest of all college football teams from the state of New York.
Syracuse's 2025 class consisted of 35 signees. The class was ranked 11th in the ACC and 41st nationally by the 247Sports Composite.