The 2025 South Carolina State Bulldogs football team represented South Carolina State University as a member of the Mid-Eastern Athletic Conference (MEAC) during the 2025 NCAA Division I FCS football season. The Bulldogs were led by second-year head coach Chennis Berry. South Carolina State played their home games at Oliver C. Dawson Stadium in Orangeburg, South Carolina.
The South Carolina State Bulldogs drew an average home attendance of 12,702, the 15th-highest of all NCAA Division I FCS football teams.