The 2025 SANFL season (officially known as the SANFL Hostplus League for sponsorship reasons) was the 146th season of the South Australian National Football League (SANFL), the highest-level Australian rules football competition in South Australia. The season began on 28 March and concluded on 21 September.
The player acquisition and list rules for the league's AFL clubs, and , were modified by the South Australian Football Commission ahead of the 2025 season. The AFL clubs will be able to access state Under-18 Academy players for a four-week period after the AFL National Championships. Both clubs will be able to sign up to six SANFL players aged 20 years or under, via an expanded Talent Development List protocol, plus two players from interstate. The long-standing sole marquee player permit was abolished, with the clubs now able to list up to four players aged over 21 from SANFL clubs, or from interstate competitions such as the VFL, WAFL or AFL. The changes were adopted following months of speculation that Port Adelaide and Adelaide would seek to move to the VFL or expedite the formation of a national reserves competition, due to a perceived view the SANFL rules for the AFL clubs had hampered player development and prevented an even competition.
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(R) = Reserves for AFL Seniors
Two interstate representative matches were arranged by the league. A match between the SANFL and VFL in Tanunda in the Barossa Valley region was scheduled during the AFL's Gather Round fixtures in South Australia. The SANFL and WAFL are also scheduled to compete in the state team's 100th match the following month in Adelaide.