The 2025 Perpetual NSW Open, was a combined men's and women's tennis tournament played on outdoor hard courts. It was the fifth edition of the tournament which was part of the 2025 ATP Challenger Tour and the eleventh edition of the tournament which was part of the 2025 ITF Women's World Tennis Tour. It took place in Sydney, Australia between 17 and 23 November 2025.
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as a special exempt:
The following player received entry into the singles main draw through the Junior Accelerator programme:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw: