The 2025 Mississippi House of Representatives special election was held on November 4, 2025, to elect 5 of 122 members of the Mississippi House of Representatives. Special elections were called in 5 districts due to court-ordered redistricting, in addition to special elections held on April 22 to fill vacancies in two districts. Primary elections were held on August 5, and runoff elections were canceled as all elections resulted in majority wins.
The election was called after court-ordered redistricting caused the state House map to be redrawn, as it was found to diminish the voting power of the state's African American population. The new map creates one new majority black district in Chickasaw County.