The 2025 Memphis Tigers football team represented the University of Memphis as a member of the American Conference during the 2025 NCAA Division I FBS football season. Led during the regular season by sixth-year head coach Ryan Silverfield, the Tigers played home games at Simmons Bank Liberty Stadium in Memphis, Tennessee.
For their bowl appearance, the team was led by interim head coach Reggie Howard, appointed following the departure of Silverfield, who was hired by the Arkansas Razorbacks.
The Memphis Tigers drew an average home attendance of 30,097, the 75th-highest of all college football teams.