In July 2025, the Italy national rugby union team toured South Africa as part of the Summer International calendar. The two-test tour was confirmed in October 2024, with a match against Namibia being included on the tour.
It was Italy's third tour of South Africa, and the first time both teams have played each other at Loftus Versfeld Stadium and Nelson Mandela Bay Stadium.
On May 21, Italy named a 33-player squad for the tour.
On June 11 Louis Lynagh replaced Monty Ioane. On June 23 Simone Ferrari replaced Giosuè Zilocchi. On June 27 it was announced that Federico Mori will not join the tour, due to injury. On June 30, Pietro Ceccarelli and Damiano Mazza were added to the squad in substitution of Marco Riccioni and Leonardo Marin, who were both injured in the first match against Namibia. On July 4, Leonard Krumov joined the team in South Africa in substitution of injured Riccardo Favretto. On July 7, Giampietro Ribaldi was called to replace Giacomo Nicotera.
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