The 2025 Holy Cross Crusaders football team represented the College of the Holy Cross as a member of the Patriot League during the 2025 NCAA Division I FCS football season. The Crusaders were led by second-year head coach Dan Curran and played at the Fitton Field in Worcester, Massachusetts.
The Holy Cross Crusaders drew an average home attendance of 13,931, the 13th-highest of all NCAA Division I FCS football teams.