The 2025 Hellenic Championship, also known as the Vanda Pharmaceutical Hellenic Championship for sponsorship reasons, was the inaugural edition of the ATP 250 Hellenic Championship. The event was played on indoor hardcourts at the OAKA Basketball Arena, a multi-purpose venue that was used for the 2004 Summer Olympics, in Athens, Greece. It replaced the Belgrade Open on the calendar. The event took place from 2 November to 8 November 2025.
per team
The following players received wildcards into the singles main draw:
The following player received a late entry into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
The following pairs received wildcards into the doubles main draw: