The 2025 FC Astana season was the seventeenth successive season that FC Astana will play in the Kazakhstan Premier League, the highest tier of association football in Kazakhstan. The finished the season as runners-up to Kairat having drawn 1-1 in the last game of the season. In the Kazakhstan Cup they reached the Quarterfinals before being knocked out by Zhenis and in the Conference League they were knocked out in the Third qualifying round by Lausanne-Sport.
On 19 January, Astana announced that Barnes Osei would be leaving the club after his contract had expired, and they had not exercised their option to extended it for an additional year.
On 2 July, Astana announced the signing of Ivan Baà ¡iàafter he had left Orenburg.
On 9 July, Astana announced that Nnamdi Ahanonu had joined Kyzylzhar on loan for the remainder of the season.
On 11 July, Astana announced the signing of Driton Camaj after he had left Kecskeméti.
On 26 July, Astana announced the signing of Bauyrzhan Islamkhan from Turan.
|- |colspan="18"|Players away from Astana on loan:
|- |colspan="18"|Players who left Astana during the season: