2025 Eastern Illinois Panthers football team

The 2025 Eastern Illinois Panthers football team represented Eastern Illinois University as a member of the OVC–Big South Football Association during the 2025 NCAA Division I FCS football season. The Panthers were led by fourth-year head coach Chris Wilkerson and played their home games at O'Brien Field located in Charleston, Illinois.

Offseason

Preseason poll

The Big South-OVC Conference released their preseason poll on July 16, 2025. The Panthers were picked to finish sixth in the conference.

Transfers

Outgoing

Incoming

Recruiting class

Schedule

Game summaries

vs. Dayton

at Indiana State

vs. No. 7 Illinois State (Mid-America Classic)

at Western Illinois

vs. Tennessee State

vs. Gardner–Webb

at Southeast Missouri State

at Charleston Southern

vs. UT Martin

vs. No. 5 Tennessee Tech

at Lindenwood

at No. 10 (FBS) Alabama

References