A nonbinding referendum was held in the Cayman Islands on 30 April 2025, alongside the general election. Voters were asked three questions.
The Association for Cruise Tourism (ACT), a coalition of stakeholders in the tourism industry, have led a campaign to promote the 'yes' vote on the question that, if passed, would allow the government to build cruise berthing facilities. Cruise Port Referendum (CPR) Cayman, a group advocating for environmentally-conscious tourism, has led the campaign to vote 'no'. On 11 April 2025, CPR Cayman accused the ACT in a press release of using misleading ads in their campaign. Elections Supervisor Wesley Howell responded to CPR's concerns by stating:
Voters rejected a proposal to build cruise ship berths, but approved the creation of a national lottery and the decriminalisation of possession of small amounts of cannabis.