The 2025 Arkansas State Red Wolves football team represented Arkansas State University in the Sun Belt Conference's West Division during the 2025 NCAA Division I FBS football season. The Red Wolves were led by Butch Jones in his fifth year as the head coach. The Red Wolves played home games at Centennial Bank Stadium, located in Jonesboro, Arkansas. On September 6, the Red Wolves played the Arkansas Razorbacks for the first time ever. The game was played in Little Rock at War Memorial Stadium.
In the Sun Belt preseason coaches' poll, the Red Wolves were picked to finish third place in the West division.
Kicker Clune Van Andel was named the Preseason Special Teams Player of the Year.
Wide receiver Corey Rucker and defensive lineman Bryan Whitehead were awarded to be in the preseason All-Sun Belt first team offense and defense. Kicker Clune Van Andel and associated press player Ja'Quez Cross were named to the All-Sun Belt first team special teams.
Running back Ja'Quez Cross was named in the second team offense and special teams.