The 2024 United States Senate election in Mississippi was held on November 5, 2024, to elect a member of the United States Senate to represent the state of Mississippi. Incumbent Senator Roger Wicker took office on December 31, 2007, as an interim appointee after Trent Lott resigned 13 days prior. Wicker retained his Senate seat in the subsequent 2008 special election, won full terms in 2012 and 2018, and sought a third full term. Primary elections took place on March 12, 2024.
Mississippi has been represented in the U.S. Senate exclusively by Republicans since 1989. Wicker easily won re-election to a third full term. Wicker improved on his performance and flipped Issaquena, Jasper, and Marshall Counties from 2018.
Wicker won three of four congressional districts.
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