The 2022 Trofeo Alfredo Binda-Comune di Cittiglio was an Italian road cycling one-day race that took place on 20 March. It was the 46th edition of Trofeo Alfredo Binda and the 3rd event of the 2022 UCI Women's World Tour. The race started in Cocquio-Trevisago and finished in Cittiglio, on the outskirts of Lago Maggiore in Northwest Italy. The race was won by the world champion Elisa Balsamo of in a sprint finish.
24 teams took part in the race. The Human Powered Health and Uno-X Pro Cycling WorldTeams did not participate in this race.
UCI Women's WorldTeams
UCI Women's Continental Teams