The 2022 San Jose State Spartans football team represented San Jose State University as a member of the Mountain West Conference during the 2022 NCAA Division I FBS football season. They were led by head coach Brent Brennan, who was coaching his sixth season with the program. The Spartans played their home games at CEFCU Stadium in San Jose, California.
On October 21, San Jose State freshman running back Camdan McWright was struck by a school bus, sustaining fatal injuries. The following day's game between the Spartans and the New Mexico State Aggies was postponed to allow San Jose State players time to grieve before the game was outright canceled.
San Jose State and the Mountain West Conference announced the 2022 football schedule on February 16, 2022.
The following individuals received postseason awards and honors as voted by the Mountain West Conference football coaches at the end of the season.
The following players were selected as part of the Mountain West's All-Conference Teams.
On October 9, San Jose State received votes in the AP Poll and Coaches Poll for the first time since the 2020 postseason.