The 2022 Pittsburgh Panthers football team represented the University of Pittsburgh as a member of the Coastal Division of the Atlantic Coast Conference (ACC) during the 2022 NCAA Division I FBS football season. The Panthers were led by eighth-year head coach Pat Narduzzi and played their home games at Acrisure Stadium in Pittsburgh. This was Pitt's tenth season as a member of the ACC.
The Panthers have signed a total of 12 student-athletes on Early National Signing Day (December 2021)