The 2022 Open Sud de France was a tennis tournament played on indoor hard courts. It was the 35th edition of the event, and part of the ATP Tour 250 series of the 2022 ATP Tour. It took place at the Arena Montpellier in Montpellier, France, from 31 January until 6 February 2022. Sixth-seeded Alexander Bublik won the singles title.
This was Bublik's maiden ATP Tour singles title.
<sub>*per team</sub>
The following players received wildcards into the singles main draw :
The following player received entry using a protected ranking into the singles main draw:
The following players received entry from the qualifying draw:
The following pairs received wildcards into the doubles main draw:
The following pair received entry using a protected ranking into the doubles main draw: