The 2022 North Texas Mean Green football team represented the University of North Texas as a member of Conference USA (C-USA) during the 2022 NCAA Division I FBS football season. Led by Seth Littrell in his seventh and final season as head coach for first 13 games of the season and interim head coach Phil Bennett for the team's bowl game, the Mean Green compiled an overall record of 7âÂÂ7 with a mark 6âÂÂ2 in conference play, tying for second place in the C-USA. North Texas advanced to the C-USA Championship Game, losing to UTSA. North Texas was invited to the Frisco Bowl, where the Mean Green lost to Boise State. The team played home games at Apogee Stadium in Denton, Texas.
Littrell was fired on December 4, 2022, after the loss to UTSA. The team's defensive coordinator, Phil Bennett, was appointed interim head coach for the Frisco Bowl.
North Texas and Conference USA announced the 2022 football schedule on March 30, 2022.
The Conference USA media day was held on July 27 at Globe Life Field in Arlington, Texas. The Mean Green were represented by head coach Seth Littrell, tight end Jake Roberts, and linebacker K. D. Davis. The Mean Green were predicted to finish fifth in the conference's preseason poll.