The 2022 FIM Motocross World Championship was the 66th FIM Motocross World Championship season.
In the MXGP class, Jeffrey Herlings started the season as the reigning champion after picking up his fifth world title in 2021. The reigning MX2 world champion, Maxime Renaux did not defend his title as he moved into the MXGP category after he picked up his maiden world title in the previous year.
The championship was contested over eighteen rounds in Europe, Asia and South America.
Vsevolod Brylyakov was a neutral competitor using the designation MFR (Motorcycle Federation of Russia), as the World Anti-Doping Agency implemented a ban on Russia competing at World Championships.