The Americas Zone is one of three zones of regional competition in the 2022 Billie Jean King Cup.
The eight teams were divided into two pools of four teams. The four nations finishing 1st and 2nd in their pools took part in play-offs to determine the nations advancing to the 2022 Billie Jean King Cup play-offs. The nations finishing third and last took part in a relegation play-offs, with the losing nations relegated to Group II for 2023.
The seventeen teams were divided into three pools of four teams and one pool of five teams. The four nations finishing 1st in their pools took part in play-offs to determine the two nations promoted to Group I in 2023.