The 2021 South Carolina State Bulldogs football team represented South Carolina State University as a member of the Mid-Eastern Athletic Conference (MEAC) in the 2021 NCAA Division I FCS football season. The Bulldogs, led by 20th-year head coach Oliver Pough, played their home games at Oliver C. Dawson Stadium.
On November 13, the Bulldogs clinched a berth in the Celebration Bowl; the team completed their season with a 7âÂÂ5 record and a 5âÂÂ0 record in conference play. The Bulldogs upset the SWAC champions No. 15 Jackson State 31âÂÂ10 in the Celebration Bowl, their first postseason win since the December 1994 Heritage Bowl.