The 2021 Sasol League National Championship was the 12th edition of the Sasol League National Championship since it was formed in 2009. It was held at King Zwelithini Stadium in Umlazi.
In the first semi-final Vasco Da Gama beat Croesus Ladies 4-3 via penalties after the match ended in a 1-1 draw. In the second semi-final, Nandipha Booi scored a hattrick to give City Lads a 3-2 win over Lindelani Ladies.
The highest scoring and biggest victory was a 12-3 win for City Lads against Royal Wizards.
All nine teams qualified through winning their provincial leagues.
The following were rated best in the tournament: