The 2021 Pensacola 200 was a ARCA Menards Series East race held on February 27, 2021, at the Five Flags Speedway. It was contested over 200 laps on the short track. It was the second race of the 2021 ARCA Menards Series East season. Joe Gibbs Racing driver Sammy Smith collected his first career win in the ARCA Menards Series East.
Practice was delayed due to rain, leading to the combination of the practice and qualifying sessions. Sammy Smith posted the fastest lap in practice, with a time of 17.493 seconds and a speed of gave him the pole award.