The 2021 North Texas Mean Green football team represented the University of North Texas as a member of Conference USA (C-USA) during the 2021 NCAA Division I FBS football season. Led by sixth-year head coach Seth Littrell, the Mean Green compiled an overall record of 6âÂÂ7 with a mark 5âÂÂ3 in conference play, placing third in C-USA's West Division. North Texas was invited to the inaugural Frisco Football Classic, where the Mean Green lost to the Miami RedHawks. The team played home games at Apogee Stadium in Denton, Texas.
The Mean Green started the season 1âÂÂ6 before winning five games in a row, including upset victories over UTEP and undefeated, No. 22 UTSA, to finish the regular season at 6âÂÂ6.
The Mean Green were predicted to finish in sixth place in the West Division in the Conference USA preseason poll.