Local elections were held on October 2021 to elect councilors and mayors in 80 municipalities and the City of Skopje in North Macedonia. The first round was held on 17 October, while the second round was held on 31 October. The elections were announced on 6 August 2021 by the Speaker of the Assembly Talat Xhaferi. According to the State Election Commission's calendar, the deadline for submitting candidacies for councilor and mayor lists was 11 September 2021. The election campaign lasted from 27 September to 15 October.
The Speaker of the Assembly Talat Xhaferi on 6 August 2021 scheduled the local elections for 17 October. In the next day, the State Election Commission set a deadline for submitting candidates until 11 September, while it permitted campaigning from 27 September to 15 October. During the election campaigns, Hristijan Mickoski alleged "corruption of the state by Zoran Zaev and his entourage." Women were underrepresented as mayoral candidates, with only 26 candidates being women (less than 9%), out of a total of 298 candidates.
The first round of the elections was held on 17 October. It was the first election in North Macedonia that utilised biometric fingerprint readers for the identification of voters. In the first round, mayors were elected in 34 municipalities. VMRO-DPMNE won in the first round in 22 municipalities, SDSM won in 9, and DUI in 3 municipalities. The second round occurred on 31 October. VMRO-DPMNE won 42 municipalities. Independent candidate Danela Arsovska, supported by VMRO-DPMNE, became the first woman to lead Skopje since the country's independence, winning against SDSM's Petre à  ilegov. SDSM won 16 mayor seats, DUI â 13, and Besa â 2, while DPA and LDP-DOM's coalition one each. Apart from Arsovska, three other independent candidates became mayors. DUI's Tetovo mayor Teuta Arifi was defeated by Besa's Bilal Kasami. Alliance for Albanians' Arben Taravari won a new four-year term in Gostivar. In Kumanovo, Maksim Dimitrievski won as an independent candidate, defeating SDSM's Oliver Ilievski.
Due to the negative results, Zaev resigned from his positions as leader of SDSM and prime minister. There was a motion of no confidence (submitted by VMRO-DPMNE) of the Government of North Macedonia in 11 November, but due to 60 votes, it was not voted out. Minister of Finance Dimitar KovaÃÂevski succeeded Zaev as party leader and prime minister. In March 2022, OSCE stated: "The October 2021 local elections in North Macedonia were competitive and fundamental freedoms were widely respected, but shortcomings in the legal framework underscore the need for a comprehensive reform."