The 2021 North American Formula 1000 Championship presented by EPC is the fifth season of the North American Formula 1000 Championship. The sixteen round season begins on April 1 at Carolina Motorsports Park, and ends on October 17 at Pittsburgh International Race Complex.
Last year's champion, Alex Mayer, became a four-time champion in the series, winning every season since the series' conception. Mayer was able to win another championship earning his fifth championship.