The 2021 Munster Senior Football Championship was the 2021 installment of the annual Munster Senior Football Championship organised by the Munster GAA. Kerry won the tournament beating Cork in the final.
The Munster championship is contested by all six counties in the Irish province of Munster.
The four non-finalists from the 2020 championship entered this round. The lowest ranked county to play in the quarter-finals was Waterford of Division 4.
The finalists from the 2020 championship entered this round along with the two quarter-final winners. The lowest ranked counties to play in the quarter-finals were Limerick and Tipperary of Division 3.
Kerry advanced to the 2021 All-Ireland Senior Football Championship semi-finals.