The 2021 Florida State Seminoles softball team represented Florida State University in the 2021 NCAA Division I softball season. The Seminoles were coached by Lonni Alameda, who led her thirteenth season. The Seminoles finished with a record of 49âÂÂ12âÂÂ1.
The Seminoles were invited to the 2021 NCAA Division I Softball Tournament, where they swept the NCAA Tallahassee Regional and Baton Rouge Super Regional and then completed a run to the title game of the Women's College World Series where they fell to champion Oklahoma.