The 2021 Cork Senior A Hurling Championship was the second staging of the Cork Senior A Hurling Championship since its establishment by the Cork County Board in 2020. The draw for the group stage placings took place on 29 April 2021. The championship began on 11 September 2021 and ended on 21 November 2021.
The final was played on 21 November 2021 at Páirc UàChaoimh in Cork, between Kanturk and Fr. O'Neill's, in what was their first meeting in a final. Kanturk won the match by 3âÂÂ17 to 2âÂÂ13 to claim their first championship title.
Blarney's Mark Coleman was the championship's top scorer with 1-38.
Relegated from the Cork Premier Senior Hurling Championship
Promoted from the Cork Premier Intermediate Hurling Championship
Promoted to the Cork Premier Senior Hurling Championship
Relegated to the Cork Premier Intermediate Hurling Championship
The seedings were based on final group stage positions from the 2020 championship.